Methyl (alphaE)-2-[(2,5-dimethylphenoxy)methyl]-alpha-(methoxyimino)benzeneacetate

Base Information

• Chemical Name: Methyl (alphaE)-2-[(2,5-dimethylphenoxy)methyl]-alpha-(methoxyimino)benzeneacetate
• CAS No.: 167374-38-1
• Molecular Formula: C₁₉H₂₁NO₄
• Molecular Weight: 327.38
• European Community (EC) Number: 461-290-6,605-476-9
• Mol file: 167374-38-1.mol

Synonyms:SCHEMBL7535610;DTXSID101144612;167374-38-1

Chemical Property of Methyl (alphaE)-2-[(2,5-dimethylphenoxy)methyl]-alpha-(methoxyimino)benzeneacetate

Chemical Property:

• Boiling Point: 446.3±47.0 °C(Predicted)
• Density: 1.09±0.1 g/cm3(Predicted)
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 327.14705815
• Heavy Atom Count: 24
• Complexity: 437

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2C(=NOC)C(=O)OC
• Isomeric SMILES: CC1=CC(=C(C=C1)C)OCC2=CC=CC=C2/C(=N\OC)/C(=O)OC

Technology Process of Methyl (alphaE)-2-[(2,5-dimethylphenoxy)methyl]-alpha-(methoxyimino)benzeneacetate

There total 2 articles about Methyl (alphaE)-2-[(2,5-dimethylphenoxy)methyl]-alpha-(methoxyimino)benzeneacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-Dimethylphenol (95-87-4) + (E)-methyl 2-(2-(chloromethyl)phenyl)-2-(methoxyimino)acetate (189813-45-4) → methyl 2-(2,5-dimethylphenoxymethyl)-α-methoxyiminophenylacetate (167374-38-1)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 - 50 ℃; for 64h;

Reference yield:

→ methyl 2-(2,5-dimethylphenoxymethyl)-α-methoxyiminophenylacetate (167374-38-1)

Guidance literature:

Reference yield: 89.6%

methyl 2-(2,5-dimethylphenoxymethyl)-α-methoxyiminophenylacetate (167374-38-1) → 2-(2,5-dimethylphenoxymethyl)-α-methoxyiminophenylacetohydrazide (202475-07-8)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; methanol; water;

upstream raw materials:

2,5-Dimethylphenol

(E)-methyl 2-(2-(chloromethyl)phenyl)-2-(methoxyimino)acetate

Downstream raw materials:

2-(2,5-dimethylphenoxymethyl)-α-methoxyiminophenylacetohydrazide