(1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Base Information

Chemical Name:(1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on
CAS No.:83578-88-5
Molecular Formula:C₃₅H₂₇NO₁₀
Molecular Weight:621.6
Hs Code.:

Synonyms:(1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Suppliers and Price of (1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

There total 10 articles about (1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 83603-30-9
(1R,2S,3S,4S,4aR,11bR)-1,3,4,4a,5,11b-Hexahydro-1,2,3,4-tetrahydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

: 98-88-4
benzoyl chloride

: 83578-88-5
(1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Guidance literature:: With dmap; In dichloromethane; 1) 0 deg C, 2) room temp., 1 h;
DOI:10.1002/jlac.198319830404

Reference yield:

: 83578-86-3
(1R,2S,3S,4S,4aR,11bR)-4-Benzyloxy-1,2,3,4,4a,11b-hexahydro-2,3-dihydroxy-1-nitro-6H<1,3>benzodioxolo<5,6-c><1>benzopyran-6-on

: 83578-88-5
(1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Guidance literature:: Multi-step reaction with 2 steps

1: 1) H₂, 2) anhyd. K₂CO₃ / 1) Pd/C (10 percent) / 1) methanol, room temp., 48 h, 1 bar, 2) methanol, reflux, 4 h

2: 78 percent / 4-(dimethylamino)pyridine / CH₂Cl₂ / 1) 0 deg C, 2) room temp., 1 h

With dmap; hydrogen; potassium carbonate; palladium on activated charcoal; In dichloromethane;
DOI:10.1002/jlac.198319830404

Reference yield:

: 350255-13-9
1,2:5,6-di-O-isopropylidene-α-D-glucofuranose

: 83578-88-5
(1R,2S,3S,4S,4aR,11bR)-2,3,4-Tribenzoyloxy-1,3,4,4a,5,11b-hexahydro-1-hydroxy<1,3>dioxolo<4,5-j>phenanthridin-6(2H)-on

Guidance literature:: Multi-step reaction with 8 steps

4: 1.) butyllithium / 2.) -110 grad C

5: 1.) 50percent acetic acid, 2.) NaHCO₃ / 2.) methanol

6: H₂/cat.

7: potassium carbonate / methanol / Heating

8: 4-dimethylamino-pyridine / pyridine / 0 °C

With Simazine; n-butyllithium; hydrogen; sodium hydrogencarbonate; potassium carbonate; acetic acid; dmap; In pyridine; methanol;
DOI:10.1016/S0040-4039(00)88587-1