VPC₁₄₃₁₄₄

Base Information

• Chemical Name: VPC₁₄₃₁₄₄
• CAS No.: 1266665-24-0
• Molecular Formula: C₂₂H₄₁N₃O₂*ClH
• Molecular Weight: 416.047
• Mol file: 1266665-24-0.mol

Synonyms:VPC₁₄₃₁₄₄

Chemical Property of VPC₁₄₃₁₄₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of VPC₁₄₃₁₄₄

There total 9 articles about VPC₁₄₃₁₄₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

1-cyano-N-(10-(cyclohexylmethoxy)decyl)cyclopropanecarboxamide (1266666-31-2) → VPC143144 (1266665-24-0)

Guidance literature:

1-cyano-N-(10-(cyclohexylmethoxy)decyl)cyclopropanecarboxamide; With sodium methylate; In methanol; at 20 - 50 ℃; for 24h; Inert atmosphere;

With ammonium chloride; In methanol; at 50 ℃; Inert atmosphere;

DOI:10.1021/jm2001053

Reference yield: 21.0%

→ VPC143144 (1266665-24-0)

Guidance literature:

Reference yield:

10-(cyclohexylmethoxy)decan-1-ol (1266666-28-7) → VPC143144 (1266665-24-0)

Guidance literature:

Multi-step reaction with 5 steps

1.1: triethylamine / dichloromethane / 0 °C / Reflux; Inert atmosphere

2.1: sodium azide / N,N-dimethyl-formamide / 12 h / 20 °C / Reflux; Inert atmosphere

3.1: water; triphenylphosphine / toluene / 0.5 h / Reflux

4.1: benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; triethylamine / dichloromethane; water / 4 h / 20 °C

5.1: sodium methylate / methanol / 24 h / 20 - 50 °C / Inert atmosphere

5.2: 50 °C / Inert atmosphere

With sodium azide; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; water; sodium methylate; triethylamine; triphenylphosphine; In methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; 3.1: Staudinger reaction;

DOI:10.1021/jm2001053

upstream raw materials:

C₁₇H₃₅NO

1-cyano-cyclopropanecarboxylic acid

((dec-9-en-1-yloxy)methyl)cyclohexane

10-(cyclohexylmethoxy)decan-1-ol