1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole

Base Information

• Chemical Name: 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole
• CAS No.: 1334027-00-7
• Molecular Formula: C₂₂H₂₂FOP
• Molecular Weight: 352.388
• Mol file: 1334027-00-7.mol

Synonyms:1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole

Chemical Property of 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole

There total 3 articles about 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

1-benzyl-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphospholium bromide → 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole (1334027-00-7)

Guidance literature:

With potassium fluoride; In dichloromethane; at 20 ℃;

DOI:10.1002/hc.20717

Reference yield:

1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole (78175-94-7) → 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole (1334027-00-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 1 h / 20 °C

2: potassium fluoride / dichloromethane / 20 °C

With potassium fluoride; In diethyl ether; dichloromethane;

DOI:10.1002/hc.20717

Reference yield:

benzyl bromide (100-39-0) → 1-benzyl-1-fluoro-1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole (1334027-00-7)

Guidance literature:

Multi-step reaction with 2 steps

1: diethyl ether / 1 h / 20 °C

2: potassium fluoride / dichloromethane / 20 °C

With potassium fluoride; In diethyl ether; dichloromethane;

DOI:10.1002/hc.20717

upstream raw materials:

benzyl bromide

1-phenyl-3,3-dimethyl-3H-2,1-benzoxaphosphole