N-[7-(4-Fluorobenzyl)-9-Hydroxy-8-Oxo-7,8-Dihydro-6h-Pyrrolo[3,4-G]quinolin-5-Yl]-N-Methylmethanesulfonamide

Base Information

Chemical Name:N-[7-(4-Fluorobenzyl)-9-Hydroxy-8-Oxo-7,8-Dihydro-6h-Pyrrolo[3,4-G]quinolin-5-Yl]-N-Methylmethanesulfonamide
CAS No.:915407-80-6
Molecular Formula:C₂₀H₁₈FN₃O₄S
Molecular Weight:415.445
Hs Code.:
ChEMBL ID:CHEMBL513189
Wikidata:Q27468130

Synonyms:GS-9160;CHEMBL513189;N-[7-(4-Fluorobenzyl)-9-Hydroxy-8-Oxo-7,8-Dihydro-6h-Pyrrolo[3,4-G]quinolin-5-Yl]-N-Methylmethanesulfonamide;GS9160;N-(7-(4-fluorobenzyl)-9-hydroxy-8-oxo-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-5-yl)-N-methylmethanesulfonamide;915407-80-6;SCHEMBL4652222;RJWBOLLTMJMYNV-UHFFFAOYSA-N;BDBM50483196;GS 9160;Q27468130;Methanesulfonamide, N-(7-((4-fluorophenyl)methyl)-7,8-dihydro-9-hydroxy-8-oxo-6H-pyrrolo(3,4-g)quinolin-5-yl)-N-methyl-;N-[7-[(4-fluorophenyl)methyl]-9-hydroxy-8-oxo-6H-pyrrolo[3,4-g]quinolin-5-yl]-N-methyl-methanesulfonamide;ZZV

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[7-(4-Fluorobenzyl)-9-Hydroxy-8-Oxo-7,8-Dihydro-6h-Pyrrolo[3,4-G]quinolin-5-Yl]-N-Methylmethanesulfonamide

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:4
Exact Mass:415.10020540
Heavy Atom Count:29
Complexity:722

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C1=C2CN(C(=O)C2=C(C3=C1C=CC=N3)O)CC4=CC=C(C=C4)F)S(=O)(=O)C

Technology Process of N-[7-(4-Fluorobenzyl)-9-Hydroxy-8-Oxo-7,8-Dihydro-6h-Pyrrolo[3,4-G]quinolin-5-Yl]-N-Methylmethanesulfonamide

There total 5 articles about N-[7-(4-Fluorobenzyl)-9-Hydroxy-8-Oxo-7,8-Dihydro-6h-Pyrrolo[3,4-G]quinolin-5-Yl]-N-Methylmethanesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 915407-79-3
C₃₃H₂₈FN₃O₄S

: 915407-80-6
N-(7-(4-fluorobenzyl)-9-hydroxy-8-oxo-7,8-di hydro-6H-pyrrolo[3,4-g]quinolin-5-yl)-N-methylmethanesulfonamide

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 0 ℃;

Reference yield: 78.0%

: N-(7-(4-fluorobenzyl)-8-oxo-9-(triisopropylsilyloxy)-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-5-yl)methanesulfonamide

: 77-78-1
dimethyl sulfate

: 915407-80-6
N-(7-(4-fluorobenzyl)-9-hydroxy-8-oxo-7,8-di hydro-6H-pyrrolo[3,4-g]quinolin-5-yl)-N-methylmethanesulfonamide

Guidance literature:: N-(7-(4-fluorobenzyl)-8-oxo-9-(triisopropylsilyloxy)-7,8-dihydro-6H-pyrrolo[3,4-g]quinolin-5-yl)methanesulfonamide; With potassium hydroxide; In water; acetone; at 15 - 25 ℃;

dimethyl sulfate; In water; acetone; at 15 - 25 ℃; for 0.666667h; Product distribution / selectivity;

Reference yield: 75.8%

: 915408-76-3
C₂₉H₃₈FN₃O₅SSi

: 915407-80-6
N-(7-(4-fluorobenzyl)-9-hydroxy-8-oxo-7,8-di hydro-6H-pyrrolo[3,4-g]quinolin-5-yl)-N-methylmethanesulfonamide

Guidance literature:: With triethylsilane; trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 11.5h; Product distribution / selectivity;