CID 71536

Base Information

• Chemical Name: CID 71536
• CAS No.: 54022-49-0
• Molecular Formula: C₄₆H₅₄N₄O₁₀
• Molecular Weight: 822.956
• DSSTox Substance ID: DTXSID70866377
• NCI Thesaurus Code: C152883
• Mol file: 54022-49-0.mol

Synonyms:F-leurosine;formyl leurosine;formyl-leurosine;formyl-leurosine, sulfate (1:1), (3'alpha,4'alpha)-isomer;formyl-leurosine, sulfate (2:1), (3'alpha,4'alpha)-isomer

Chemical Property of CID 71536

Chemical Property:

• Melting Point: 200-210°C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 163.47000
• Density: 1.42g/cm³
• LogP: 4.11060
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 10
• Exact Mass: 822.38399393
• Heavy Atom Count: 60
• Complexity: 1800

Purity/Quality:

99%min ^*data from raw suppliers

N-Formyl leurosine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC12CN3CCC4=C(C(CC(C3)C1O2)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)NC1=CC=CC=C41
• Uses: Degradation products of Vincristine. A Vinca dimer, a potent cytostatic agent. Vincristine Impurity G. Degradation products of Vincristine. A Vinca dimer, a potent cytostatic agent. Vincristine Impurity G

Technology Process of CID 71536

There total 1 articles about CID 71536 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

vinleurosine (23360-92-1) → 22-Oxoleurosin (54022-49-0)

Guidance literature:

With chromium(VI) oxide; In acetic anhydride; acetone; at -78 ℃;

DOI:10.1139/v78-420

upstream raw materials:

vinleurosine

Refernces