poly (arginyl-glycyl-aspartic acid)

Base Information

• Chemical Name: poly (arginyl-glycyl-aspartic acid)
• CAS No.: 119865-10-0
• Molecular Formula: C₁₂H₂₂N₆O₆
• Molecular Weight: 346.343
• Mol file: 119865-10-0.mol

Synonyms:poly (arginyl-glycyl-aspartic acid)

Chemical Property of poly (arginyl-glycyl-aspartic acid)

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.61g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of poly (arginyl-glycyl-aspartic acid)

There total 6 articles about poly (arginyl-glycyl-aspartic acid) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

Arg(Pbf)-Gly-Asp(OtBu) → Arg-Gly-Asp (99896-85-2,119865-10-0)

Guidance literature:

With methanol; triethylsilane; water; trifluoroacetic acid; at 20 ℃; for 2h;

DOI:10.1002/cmdc.201800704

Reference yield: 54.0%

glycyl-L-aspartic acid (4685-12-5) + Nα,NG,NG'-tri-Boc-L-arginine N-hydroxysuccinimide ester (108787-79-7) → Arg-Gly-Asp (99896-85-2,119865-10-0)

Guidance literature:

glycyl-L-aspartic acid; N^α,N^G,N^G'-tri-Boc-L-arginine N-hydroxysuccinimide ester; With 4-methyl-morpholine; In N,N-dimethyl-formamide; at 20 ℃; for 24h;

With trifluoroacetic acid; In chloroform;

DOI:10.1007/BF02464250

Reference yield:

p-cresol (106-44-5) + thiophenol (108-98-5) → Arg-Gly-Asp (99896-85-2,119865-10-0)

Guidance literature:

In hydrogen fluoride;

upstream raw materials:

glycyl-L-aspartic acid

N^α,N^G,N^G'-tri-Boc-L-arginine N-hydroxysuccinimide ester

N-(fluoren-9-ylmethoxycarbonyl)glycine

Fmoc-(tBu)Asp-OH