(R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

Base Information

Chemical Name:(R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate
CAS No.:923984-36-5
Molecular Formula:C₂₄H₃₁NO₃
Molecular Weight:381.515
Hs Code.:

Synonyms:(R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

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Technology Process of (R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

There total 2 articles about (R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 5292-43-3
bromoacetic acid tert-butyl ester

: 85864-33-1
phenyl(2-pivaloylamidophenyl)methane

: 923984-36-5
(R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

Guidance literature:: phenyl(2-pivaloylamidophenyl)methane; With n-butyllithium; (-)-sparteine; In various solvent(s); at -15 ℃; for 1h;

bromoacetic acid tert-butyl ester; In various solvent(s); at -15 ℃; for 0.166667h; Further stages.;
DOI:10.1055/s-2006-950299

Reference yield:

: 5292-43-3
bromoacetic acid tert-butyl ester

: 85864-33-1
phenyl(2-pivaloylamidophenyl)methane

: 923984-36-5
(R)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

: (S)-tert-butyl 3-{2-[(2,2-dimethylpropanoyl)amino]phenyl}-3-phenylpropanoate

Guidance literature:: phenyl(2-pivaloylamidophenyl)methane; With n-butyllithium; (-)-sparteine; In various solvent(s); at -15 ℃;

bromoacetic acid tert-butyl ester; In various solvent(s); at -78 ℃; Further stages. Title compound not separated from byproducts.;
DOI:10.1055/s-2006-950299