1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Base Information

Chemical Name:1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester
CAS No.:1394019-95-4
Molecular Formula:C₂₈H₃₇NO₄
Molecular Weight:451.606
Hs Code.:

Synonyms:1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Suppliers and Price of 1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

There total 4 articles about 1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1394019-93-2
C₂₇H₃₅NO₄

: 1774-47-6
trimethylsulfoxonium iodide

: 1394019-95-4
1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Guidance literature:: trimethylsulfoxonium iodide; With sodium hydride; In dimethyl sulfoxide; at 20 ℃; for 0.25h;

C₂₇H₃₅NO₄; In dimethyl sulfoxide; at 20 ℃;

Reference yield:

: 2033-24-1
cycl-isopropylidene malonate

: 128779-47-5
(2R)-3-(biphenyl-4-yl)-2-[(tert-butoxycarbonyl)amino]propanoic acid

: 1394019-95-4
1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 6.5 h / 0 °C

1.2: 3.5 h / 0 °C

1.3: 65 °C

2.1: sodium hydride / dimethyl sulfoxide / 0.25 h / 20 °C

2.2: 20 °C

With dmap; sodium hydride; dicyclohexyl-carbodiimide; In dichloromethane; dimethyl sulfoxide;

Reference yield:

: 2033-24-1
cycl-isopropylidene malonate

: 1394019-95-4
1-((R)-3-biphenyl-4-yl-2-t-butoxycarbonylaminopropyl)cyclopropanecarboxylic acid t-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: dmap; dicyclohexyl-carbodiimide / dichloromethane / 6.5 h / 0 °C / Inert atmosphere

1.2: 3.5 h / 0 °C / Inert atmosphere

1.3: 65 °C

2.1: sodium hydride / dimethyl sulfoxide / 0.25 h / 20 °C / Inert atmosphere

2.2: 20 °C

With dmap; sodium hydride; dicyclohexyl-carbodiimide; In dichloromethane; dimethyl sulfoxide;