tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Base Information

Chemical Name:tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside
CAS No.:385421-83-0
Molecular Formula:C₂₆H₃₉N₃O₈Si
Molecular Weight:549.696
Hs Code.:

Synonyms:tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Suppliers and Price of tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

There total 3 articles about tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 123-76-2
levulinic acid

: 385422-22-0
3-O-acetyl-2-azido-6-O-benzyl-2-deoxy-1-O-tert-butyldimethylsilyl-β-D-glucopyranoside

: 385421-83-0
tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Guidance literature:: levulinic acid; With dmap; bis-2-propyl carbonate; In dichloromethane; at 0 ℃;

3-O-acetyl-2-azido-6-O-benzyl-2-deoxy-1-O-tert-butyldimethylsilyl-β-D-glucopyranoside; In dichloromethane; at 20 ℃; for 12h; Further stages.;
DOI:10.1021/jo015987h

Reference yield:

: 138923-10-1
2-azido-4,6-O-benzylidene-2-deoxyl-1-O-tert-butyldimethylsilyl-β-D-glucopyranoside

: 385421-83-0
tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: 90 percent / DMAP / CH₂Cl₂ / 0.5 h

2.1: 91 percent / trifluoroacetic acid; triethylsilane / CH₂Cl₂ / 3 h / 20 °C

3.1: DIPC; DMAP / CH₂Cl₂ / 0 °C

3.2: 92 percent / CH₂Cl₂ / 12 h / 20 °C

With triethylsilane; dmap; bis-2-propyl carbonate; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jo015987h

Reference yield:

: 385422-21-9
3-O-acetyl-2-azido-1-O-tert-butyldimethylsilyl-2-deoxy-4,6-O-benzylidene-β-D-glucopyranoside

: 385421-83-0
tert-butyldimethylsilyl 3-O-acetyl-6-O-benzyl-2-deoxy-2-azido-4-O-levulinyl-β-D-glucopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1.1: 91 percent / trifluoroacetic acid; triethylsilane / CH₂Cl₂ / 3 h / 20 °C

2.1: DIPC; DMAP / CH₂Cl₂ / 0 °C

2.2: 92 percent / CH₂Cl₂ / 12 h / 20 °C

With triethylsilane; dmap; bis-2-propyl carbonate; trifluoroacetic acid; In dichloromethane;
DOI:10.1021/jo015987h