Technology Process of 2-(2'-hydroxyethyl)-5-methylcarboxylate-1,4-benzoquinone
There total 10 articles about 2-(2'-hydroxyethyl)-5-methylcarboxylate-1,4-benzoquinone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
ammonium cerium(IV) nitrate;
In
water; acetonitrile;
for 0.0833333h;
DOI:10.1021/jo000696e
- Guidance literature:
-
Multi-step reaction with 9 steps
1.1: potassium carbonate; tetra-n-butylammonium iodide / acetone / Heating
2.1: sodium hydride / tetrahydrofuran / 0 °C
3.1: 93 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
4.1: 65 percent / N,N-diethylaniline / 4 h / Heating
5.1: 94 percent / tetra-n-butylammonium iodide; potassium hydroxide / dimethylformamide / 18 h
6.1: MnO2 / CH2Cl2 / 10 h
6.2: 88 percent / NaCN; acetic acid; MnO2 / 20 h
7.1: OsO4; NaIO4 / diethyl ether; acetone; H2O / 10 h / 24 - 26 °C
7.2: sodium borohydride / methanol / 0.5 h / 0 °C
8.1: 96 mg / hydrogen / Pd/C / ethanol / 16 h
9.1: 64 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.08 h
With
manganese(IV) oxide; potassium hydroxide; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; ammonium cerium(IV) nitrate; hydrogen; tetra-(n-butyl)ammonium iodide; sodium hydride; potassium carbonate; N,N-diethylaniline;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; acetonitrile;
4.1: Claisen rearrangement;
DOI:10.1021/jo000696e
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: sodium hydride / tetrahydrofuran / 0 °C
2.1: 93 percent / LiAlH4 / tetrahydrofuran / 1 h / 0 °C
3.1: 65 percent / N,N-diethylaniline / 4 h / Heating
4.1: 94 percent / tetra-n-butylammonium iodide; potassium hydroxide / dimethylformamide / 18 h
5.1: MnO2 / CH2Cl2 / 10 h
5.2: 88 percent / NaCN; acetic acid; MnO2 / 20 h
6.1: OsO4; NaIO4 / diethyl ether; acetone; H2O / 10 h / 24 - 26 °C
6.2: sodium borohydride / methanol / 0.5 h / 0 °C
7.1: 96 mg / hydrogen / Pd/C / ethanol / 16 h
8.1: 64 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.08 h
With
manganese(IV) oxide; potassium hydroxide; sodium periodate; osmium(VIII) oxide; lithium aluminium tetrahydride; ammonium cerium(IV) nitrate; hydrogen; tetra-(n-butyl)ammonium iodide; sodium hydride; N,N-diethylaniline;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide; acetone; acetonitrile;
3.1: Claisen rearrangement;
DOI:10.1021/jo000696e
