2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol

Base Information

• Chemical Name: 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol
• CAS No.: 1227408-26-5
• Molecular Formula: C₃₇H₄₆N₂O₂
• Molecular Weight: 550.784
• Mol file: 1227408-26-5.mol

Synonyms:2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol

Chemical Property of 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol

There total 3 articles about 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

OCH3C6H4CHNCH2CH2N(CH3)2 → 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol (1227408-26-5)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tetrahydroborate / methanol / 12 h / 0 °C / Inert atmosphere

2: methanol / 12 h / 80 °C / Inert atmosphere

With sodium tetrahydroborate; In methanol; 2: Mannich reaction;

DOI:10.1039/c0dt00250j

Reference yield:

ortho-anisaldehyde (135-02-4) → 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol (1227408-26-5)

Guidance literature:

Multi-step reaction with 3 steps

1: methanol / 24 h / Inert atmosphere; Reflux

2: sodium tetrahydroborate / methanol / 12 h / 0 °C / Inert atmosphere

3: methanol / 12 h / 80 °C / Inert atmosphere

With sodium tetrahydroborate; In methanol; 3: Mannich reaction;

DOI:10.1039/c0dt00250j

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,4-di-cumylphenol (2772-45-4,106060-52-0) + N'-(2-methoxy-benzyl)-N,N-dimethyl-ethylenediamine (626216-36-2) → 2-(N-(2-methoxybenzyl)-N-[2-(N,N-dimethyl)aminoethyl]aminomethyl)-4,6-dicumylphenol (1227408-26-5)

Guidance literature:

In methanol; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1039/c0dt00250j

upstream raw materials:

formaldehyd

2,4-di-cumylphenol

N'-(2-methoxy-benzyl)-N,N-dimethyl-ethylenediamine

ortho-anisaldehyde