tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

Base Information

Chemical Name:tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate
CAS No.:1253390-83-8
Molecular Formula:C₂₆H₂₅N₇O₃
Molecular Weight:483.53
Hs Code.:

Synonyms:tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

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Chemical Property of tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

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Technology Process of tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

There total 1 articles about tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1253390-69-0
tert-butyl allyl-(7-amino-4-(benzyloxy)-6-formylpyrido[2,3-d]pyrimidin-2-yl)carbamate

: 109-77-3
malononitrile

: 1253390-83-8
tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

Guidance literature:: With pyridine; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1021/jo101194v

Reference yield: 77.0%

: 1253390-83-8
tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

: 4461-33-0
benzoyl isocyanate

: 1253390-85-0
tert-butyl allyl(4-(benzyloxy)-7-cyano-8-(3-phenylcarbonylureido)pyrimido[4,5-b][1,8]naphthyridine)carbamate

Guidance literature:: tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate; benzoyl isocyanate; In dichloromethane; at 0 ℃; Inert atmosphere;

With water-d2; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1021/jo101194v

Reference yield: 77.0%

: 1253390-83-8
tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate

: 3019-71-4
Trichloroacetyl isocyanate

: 1253390-84-9
tert-butyl allyl(4-(benzyloxy)-7-cyano-8-ureidopyrimido[4,5-b][1,8]naphthyridine)carbamate

Guidance literature:: tert-butyl allyl(8-amino-4-(benzyloxy)-7-cyanopyrimido[4,5-b][1,8]naphthyridine)carbamate; Trichloroacetyl isocyanate; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;

With ammonia; isopropyl alcohol; In dichloromethane; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1021/jo101194v