((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Base Information

Chemical Name:((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane
CAS No.:947395-44-0
Molecular Formula:C₂₇H₄₂O₄Si
Molecular Weight:458.714
Hs Code.:

Synonyms:((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Suppliers and Price of ((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

There total 4 articles about ((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 947395-43-9
4-(2,5-bis((2-methoxyethoxy)methyl)-4-((triisopropylsilyl)ethynyl)phenyl)-2-methylbut-3-yn-2-ol

: 947395-44-0
((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Guidance literature:: With sodium hydroxide; In toluene; at 80 ℃; for 3h;
DOI:10.1021/ol071006x

Reference yield:

: 35335-16-1
1,4-bis(bromomethyl)-2,5-dibromobenzene

: 947395-44-0
((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Guidance literature:: Multi-step reaction with 4 steps

1: 76 percent / sodium / benzene / 0 - 70 °C

2: 56 percent / CuI; triethylamine / PdCl₂(PPh₃)2 / tetrahydrofuran / 3 h / 50 °C

3: 93 percent / CuI; triethylamine / PdCl₂(PPh₃)2 / dimethylformamide / 16 h / 45 °C

4: 66 percent / NaOH / toluene / 3 h / 80 °C

With sodium hydroxide; copper(l) iodide; sodium; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; N,N-dimethyl-formamide; toluene; benzene; 2: Sonogashira coupling / 3: Sonogashira coupling;
DOI:10.1021/ol071006x

Reference yield:

: 947395-41-7
4-(4-bromo-2,5-bis((2-methoxyethoxy)methyl)phenyl)-2-methylbut-3-yn-2-ol

: 947395-44-0
((4-ethynyl-2,5-bis((2-methoxyethoxy)methyl)phenyl)ethynyl)triisopropylsilane

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / CuI; triethylamine / PdCl₂(PPh₃)2 / dimethylformamide / 16 h / 45 °C

2: 66 percent / NaOH / toluene / 3 h / 80 °C

With sodium hydroxide; copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In N,N-dimethyl-formamide; toluene; 1: Sonogashira coupling;
DOI:10.1021/ol071006x