4-(Trimethylsilyl)benzhydrol

Base Information

Chemical Name:4-(Trimethylsilyl)benzhydrol
CAS No.:17964-15-7
Molecular Formula:C₁₆H₂₀OSi
Molecular Weight:256.42
Hs Code.:
European Community (EC) Number:659-444-4

Synonyms:4-(TRIMETHYLSILYL)BENZHYDROL;Phenyl(4-(trimethylsilyl)phenyl)methanol;17964-15-7;AKOS024338483

Suppliers and Price of 4-(Trimethylsilyl)benzhydrol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-(Trimethylsilyl)benzhydrol

Chemical Property:

Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:256.128341792
Heavy Atom Count:18
Complexity:244

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C[Si](C)(C)C1=CC=C(C=C1)C(C2=CC=CC=C2)O

Technology Process of 4-(Trimethylsilyl)benzhydrol

There total 1 articles about 4-(Trimethylsilyl)benzhydrol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 17964-15-7
4-trimethylsilanyl-benzhydrol

Guidance literature:: /BRN= 3292335/;
DOI:10.1021/jo01376a006

Reference yield: 82.0%

: 108-22-5
Isopropenyl acetate

: 17964-15-7
4-trimethylsilanyl-benzhydrol

: (R)-phenyl(4-(trimethylsilyl)phenyl)methyl acetate

Guidance literature:: 4-trimethylsilanyl-benzhydrol; With lipoprotein lipase-D₁; C₄₃H₃₅ClO₁₀Ru; potassium carbonate; In toluene; at 60 ℃; for 0.5h; Schlenk technique; Inert atmosphere; Enzymatic reaction;

Isopropenyl acetate; In toluene; at 40 ℃; for 72h; enantioselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1021/cs501629m

Reference yield:

: 17964-15-7
4-trimethylsilanyl-benzhydrol

: 132301-89-4
(R)-1-[2-[(4-chlorophenyl)phenylmethoxy]ethyl]piperidine

Guidance literature:: Multi-step reaction with 4 steps

1.1: C₄₃H₃₅ClO₁₀Ru; lipoprotein lipase-D₁; potassium carbonate / toluene / 0.5 h / 60 °C / Schlenk technique; Inert atmosphere; Enzymatic reaction

1.2: 72 h / 40 °C / Schlenk technique; Inert atmosphere

2.1: potassium carbonate / methanol; water / 2 h / 20 °C

3.1: potassium chloride; N-chloro-succinimide / methanol / 2 h / 60 °C

4.1: sodium hydroxide / dichloromethane / 0.33 h / 0 - 20 °C

With N-chloro-succinimide; lipoprotein lipase-D₁; C₄₃H₃₅ClO₁₀Ru; potassium chloride; potassium carbonate; sodium hydroxide; In methanol; dichloromethane; water; toluene;
DOI:10.1021/cs501629m