N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride

Base Information

• Chemical Name: N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride
• CAS No.: 132872-30-1
• Molecular Formula: C₂₂H₂₆ClNO₂
• Molecular Weight: 371.907
• Mol file: 132872-30-1.mol

Synonyms:N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride

Chemical Property of N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride

There total 4 articles about N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.5%

N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>amine (132872-29-8) + trichloroacetic acid anhydride (4124-31-6) → N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride (132872-30-1)

Guidance literature:

With pyridine; In benzene; for 96h;

DOI:10.1039/P19940000379

Reference yield:

N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>amine (132872-29-8) → N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride (132872-30-1)

Guidance literature:

With pyridine; In benzene; at 25 ℃; for 96h;

DOI:10.1016/0040-4039(91)80870-C

Reference yield:

3-(tert-butoxycarbonylamino)-5-methylhex-4-enol (132872-27-6) → N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>carbamoyl chloride (132872-30-1)

Guidance literature:

Multi-step reaction with 3 steps

1: NaH

2: pTsOH

3: pyridine / benzene / 96 h / 25 °C

With pyridine; sodium hydride; toluene-4-sulfonic acid; In benzene;

DOI:10.1016/0040-4039(91)80870-C

upstream raw materials:

N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>amine

trichloroacetic acid anhydride

3-(tert-butoxycarbonylamino)-5-methylhex-4-enol

N-benzyl-N-<1-(2'-benzyloxyethyl)-3-methylbut-2-enyl>-N-(tert-butoxycarbonyl)amine

Downstream raw materials:

trans-3-acetyl-1-benzyl-4-(2'-benzyloxyethyl)azetidin-2-one

trans-1-benzyl-4-(2'-benzyloxyethyl)-3-(1'R-hydroxyethyl)azetidin-2-one

trans-4-(2'-Benzyloxyethyl)-3-(1'-hydroxyethyl)-N-benzylazetidin-2-one

trans-3-allyl-1-benzyl-4-(2'-benzyloxyethyl)azetidin-2-one