benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Base Information

Chemical Name:benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate
CAS No.:1448441-79-9
Molecular Formula:C₂₇H₂₀ClFN₄O₃
Molecular Weight:502.932
Hs Code.:

Synonyms:benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Suppliers and Price of benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

There total 6 articles about benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.8%

: 1448441-78-8
benzyl 5-(benzyloxy)-2-((2-chlorophenyl)amino)-3,4-difluorobenzoate

: 1448441-79-9
benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 90 ℃; for 3h;

Reference yield:

: 2822-41-5
2,3,4-trifluorophenol

: 1448441-79-9
benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium carbonate / acetone / 24 h / 50 °C

2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere

2.2: 20 °C

3.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

4.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 5 h / 20 °C

5.1: sodium azide / N,N-dimethyl-formamide / 3 h / 90 °C

With n-butyllithium; sodium azide; sodium carbonate; potassium hydrogencarbonate; diisopropylamine; lithium hexamethyldisilazane; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; acetone;

Reference yield:

: 100-39-0
benzyl bromide

: 1448441-79-9
benzyl 4-azido-5-(benzyloxy)-2-((2-chlorophenyl)amino)-3-fluorobenzoate

Guidance literature:: Multi-step reaction with 5 steps

1.1: sodium carbonate / acetone / 24 h / 50 °C

2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexane / 2 h / -78 °C / Inert atmosphere

2.2: 20 °C

3.1: lithium hexamethyldisilazane / tetrahydrofuran / -78 - 20 °C / Inert atmosphere

4.1: potassium hydrogencarbonate / N,N-dimethyl-formamide / 5 h / 20 °C

5.1: sodium azide / N,N-dimethyl-formamide / 3 h / 90 °C

With n-butyllithium; sodium azide; sodium carbonate; potassium hydrogencarbonate; diisopropylamine; lithium hexamethyldisilazane; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; acetone;