3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Base Information

Chemical Name:3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester
CAS No.:868083-02-7
Molecular Formula:C₂₄H₂₅NO₈
Molecular Weight:455.464
Hs Code.:

Synonyms:3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Suppliers and Price of 3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

There total 4 articles about 3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 868082-98-8
[(S)-3-((R)-1-Hydroxy-ethyl)-4-oxo-azetidin-(2Z)-ylidene]-acetic acid benzyl ester

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 868083-02-7
3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Guidance literature:: With tin(IV) chloride; In benzene; for 4h; Heating;
DOI:10.1016/j.bmc.2005.06.041

Reference yield:

: 868082-96-6
[(S)-3-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-(2Z)-ylidene]-acetic acid benzyl ester

: 868083-02-7
3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: HCl / acetonitrile

2: SnCl₄ / benzene; CH₂Cl₂ / 4 h / Heating

With hydrogenchloride; tin(IV) chloride; In dichloromethane; acetonitrile; benzene;
DOI:10.1021/jm0580510

Reference yield:

: 86978-81-6
(3R,4R)-4-acetoxy-3-[(R)-1-(t-butyldimethylsilyloxy)ethyl]-1-trimethylsilyl-2-azetidinone

: 868083-02-7
3,4,5-Trimethoxy-benzoic acid (R)-1-{(S)-2-[1-benzyloxycarbonyl-meth-(Z)-ylidene]-4-oxo-azetidin-3-yl}-ethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 54 percent / TiCl₄ / CH₂Cl₂ / 0 - 20 °C

2: HCl / acetonitrile

3: SnCl₄ / benzene; CH₂Cl₂ / 4 h / Heating

With hydrogenchloride; titanium tetrachloride; tin(IV) chloride; In dichloromethane; acetonitrile; benzene;
DOI:10.1021/jm0580510