2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

Base Information

Chemical Name:2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane
CAS No.:207235-68-5
Molecular Formula:C₁₈H₁₈N₂O₄
Molecular Weight:326.352
Hs Code.:

Synonyms:2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

Chemical Property:

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Technology Process of 2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

There total 6 articles about 2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 207235-68-5
2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

Guidance literature:

Reference yield:

: 207235-69-6
2-benzyloxycarbonylamino-1-hydroxy-1-[5-(methoxycarbonyl)benzoxazol-2-yl]-3-phenylpropane

: 207235-68-5
2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

Guidance literature:: With hydrogen; 10percent Pd/C; In methanol; at 20 ℃; for 18h;
DOI:10.1021/jm000496v

Reference yield:

: 59830-60-3,63219-70-5,68474-26-0
N-benzyloxycarbonyl-2-amino-3-phenylpropionaldehyde

: 207235-68-5
2-amino-1-hydroxy-1-[5-(methoxy-carbonyl)benzoxazol-2-yl]-3-phenylpropane

Guidance literature:: Multi-step reaction with 4 steps

1: 94 percent / Et₃N / CH₂Cl₂ / 4 h / 20 °C

2: HCl / CHCl₃ / 3 h / 0 °C

3: ethanol / 6 h / Heating

4: H₂ / 10percent Pd/C / methanol / 18 h / 20 °C

With hydrogenchloride; hydrogen; triethylamine; 10percent Pd/C; In methanol; ethanol; dichloromethane; chloroform;
DOI:10.1021/jm000496v