2-methoxy-5-methylisophthaloyl dichloride

Base Information

• Chemical Name: 2-methoxy-5-methylisophthaloyl dichloride
• CAS No.: 197906-33-5
• Molecular Formula: C₁₀H₈Cl₂O₃
• Molecular Weight: 247.078
• Mol file: 197906-33-5.mol

Synonyms:2-methoxy-5-methylisophthaloyl dichloride

Chemical Property of 2-methoxy-5-methylisophthaloyl dichloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-methoxy-5-methylisophthaloyl dichloride

There total 3 articles about 2-methoxy-5-methylisophthaloyl dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-methoxy-5-methylbenzene-1,3-dicarboxylic acid (197906-32-4) → 2-methoxy-5-methylisophthaloyl dichloride (197906-33-5)

Guidance literature:

With thionyl chloride; for 5h; Heating;

DOI:10.1016/S0040-4020(97)00896-X

Reference yield:

2,6-bis(hydroxymethyl)-4-methylphenol (91-04-3) → 2-methoxy-5-methylisophthaloyl dichloride (197906-33-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent

2: 85 percent / KMnO₄

3: 99 percent / SOCl₂ / 5 h / Heating

With potassium permanganate; thionyl chloride;

DOI:10.1016/S0040-4020(97)00896-X

Reference yield:

2,6-bis(hydroxymethyl)-4-methyl-anisole (6327-85-1) → 2-methoxy-5-methylisophthaloyl dichloride (197906-33-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 85 percent / KMnO₄

2: 99 percent / SOCl₂ / 5 h / Heating

With potassium permanganate; thionyl chloride;

DOI:10.1016/S0040-4020(97)00896-X

upstream raw materials:

2-methoxy-5-methylbenzene-1,3-dicarboxylic acid

2,6-bis(hydroxymethyl)-4-methylphenol

2,6-bis(hydroxymethyl)-4-methyl-anisole

Downstream raw materials:

[2-Methoxy-5-methyl-3-(2-thioxo-thiazolidine-3-carbonyl)-phenyl]-(2-thioxo-thiazolidin-3-yl)-methanone

Refernces