1-benzyl-2-aziridine carboxaldehyde

Base Information

Chemical Name:1-benzyl-2-aziridine carboxaldehyde
CAS No.:30005-72-2
Molecular Formula:C₁₀H₁₁NO
Molecular Weight:161.203
Hs Code.:

Synonyms:1-benzyl-2-aziridine carboxaldehyde

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Chemical Property of 1-benzyl-2-aziridine carboxaldehyde

Chemical Property:

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Technology Process of 1-benzyl-2-aziridine carboxaldehyde

There total 5 articles about 1-benzyl-2-aziridine carboxaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 63226-81-3
1-phenylmethyl-2-hydroxymethylaziridine

: 30005-72-2
1-benzyl-2-aziridine carboxaldehyde

Guidance literature:: 1-phenylmethyl-2-hydroxymethylaziridine; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.75h; Inert atmosphere; Schlenk technique;

With triethylamine; In dichloromethane; at -78 - 20 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1002/asia.201600907

Reference yield:

: 34943-06-1
1-benzylaziridine-2-carboxylic acid ethyl ester

: 30005-72-2
1-benzyl-2-aziridine carboxaldehyde

Guidance literature:: With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 ℃; for 1.5h; Inert atmosphere;
DOI:10.1002/chem.201302029

Reference yield:

: 100-46-9
benzylamine

: 30005-72-2
1-benzyl-2-aziridine carboxaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / ethanol / 16 h / 0 - 60 °C / Inert atmosphere

2: diisobutylaluminium hydride / toluene; dichloromethane / 1.5 h / -78 °C / Inert atmosphere

With diisobutylaluminium hydride; triethylamine; In ethanol; dichloromethane; toluene;
DOI:10.1002/chem.201302029