N-ethyl-2,4-dimethylbenzenesulfonamide

Base Information

• Chemical Name: N-ethyl-2,4-dimethylbenzenesulfonamide
• CAS No.: 257953-14-3
• Molecular Formula: C₁₀H₁₅NO₂S
• Molecular Weight: 213.301
• Mol file: 257953-14-3.mol

Synonyms:N-ethyl-2,4-dimethylbenzenesulfonamide

Chemical Property of N-ethyl-2,4-dimethylbenzenesulfonamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-ethyl-2,4-dimethylbenzenesulfonamide

There total 1 articles about N-ethyl-2,4-dimethylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

N-ethyl-4-methyl-benzenesulfonamide (80-39-7) + methyl iodide (74-88-4) → N-ethyl-2,4-dimethylbenzenesulfonamide (257953-14-3)

Guidance literature:

N-ethyl-4-methyl-benzenesulfonamide; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; hexane; at 0 ℃; for 1h; Further stages.;

DOI:10.1021/jo001402s

Reference yield: 66.0%

N-ethyl-2,4-dimethylbenzenesulfonamide (257953-14-3) → 2,4-dimethylbenzenesulfonamide (7467-12-1)

Guidance literature:

With [bis(acetoxy)iodo]benzene; iodine; In 1,2-dichloro-ethane; at 30 - 40 ℃; for 3h; Irradiation;

Reference yield: 40.0%

N-ethyl-2,4-dimethylbenzenesulfonamide (257953-14-3) → 2-Ethyl-5-methyl-3-oxo-benzisothiazolin-1,1-dioxid (92681-07-7) + N-ethyl-5-methyl-1,2-benzisothiazoline-3-one-1-oxide (257953-00-7)

Guidance literature:

With [bis(acetoxy)iodo]benzene; iodine; In 1,2-dichloro-ethane; at 25 - 35 ℃; for 2h; irradiation with high-pressure mercury lamp;

DOI:10.1016/S0040-4020(99)00974-6

upstream raw materials:

N-ethyl-4-methyl-benzenesulfonamide

methyl iodide

Downstream raw materials:

2-Ethyl-5-methyl-3-oxo-benzisothiazolin-1,1-dioxid

N-ethyl-5-methyl-1,2-benzisothiazoline-3-one-1-oxide

2,4-dimethylbenzenesulfonamide

Refernces