(2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Base Information

Chemical Name:(2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate
CAS No.:354556-06-2
Molecular Formula:C₂₂H₂₉N₃O₄Si
Molecular Weight:427.575
Hs Code.:

Synonyms:(2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Suppliers and Price of (2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

There total 4 articles about (2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 58479-61-1
tert-butylchlorodiphenylsilane

: 354556-03-9
(2S,3R)-3-azido-2,4-dihydroxybutyl acetate

: 354556-06-2
(2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Guidance literature:: With 1H-imidazole;
DOI:10.1016/S0957-4166(01)00099-4

Reference yield:

: 39583-14-7
3-methylcarbonyloxymethyl-2-oxiranylmethyl acetate

: 354556-06-2
(2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Guidance literature:: Multi-step reaction with 3 steps

1: NaN₃; NH₄Cl / ethanol; H₂O / 80 °C

2: 30 percent / porcine pancreatic lipase (EC 3.1.1.3, Type II); TRIS-HCl buffer; NaCl / H₂O / 1 h / 30 °C / pH 7.2 / Enzymatic reaction

3: 89 percent / imidazole

With 1H-imidazole; sodium azide; Tris-HCl buffer; porcine pancreatic lipase (EC 3.1.1.3, Type II); ammonium chloride; sodium chloride; In ethanol; water;
DOI:10.1016/S0957-4166(01)00099-4

Reference yield:

: 25260-60-0
cis-1,4-bis(acetyloxy)but-2-ene

: 354556-06-2
(2S,3R)-3-azido-2-hydroxy-4-(tert-butyldiphenyl)silyloxybutyl acetate

Guidance literature:: Multi-step reaction with 4 steps

1: Oxone; acetone / 25 - 27 °C / pH 7.2

2: NaN₃; NH₄Cl / ethanol; H₂O / 80 °C

3: 30 percent / porcine pancreatic lipase (EC 3.1.1.3, Type II); TRIS-HCl buffer; NaCl / H₂O / 1 h / 30 °C / pH 7.2 / Enzymatic reaction

4: 89 percent / imidazole

With 1H-imidazole; Oxone; sodium azide; Tris-HCl buffer; porcine pancreatic lipase (EC 3.1.1.3, Type II); ammonium chloride; acetone; sodium chloride; In ethanol; water;
DOI:10.1016/S0957-4166(01)00099-4