Technology Process of (E)-ethyl benzyl(1-iodo-2-phenylvinyl)carbamate
There total 3 articles about (E)-ethyl benzyl(1-iodo-2-phenylvinyl)carbamate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C18H17NO2;
With
trimethylsilyl iodide;
In
dichloromethane;
at -78 ℃;
for 0.333333h;
Inert atmosphere;
With
water;
In
dichloromethane;
at -78 - 0 ℃;
for 1h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2012.12.101
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: potassium phosphate; copper(II) sulphate hydrate; 1,10-Phenanthroline / toluene / 15 h / 80 °C / Inert atmosphere
2.1: trimethylsilyl iodide / dichloromethane / 0.33 h / -78 °C / Inert atmosphere
2.2: 1 h / -78 - 0 °C / Inert atmosphere
With
potassium phosphate; 1,10-Phenanthroline; copper(II) sulphate hydrate; trimethylsilyl iodide;
In
dichloromethane; toluene;
DOI:10.1016/j.tetlet.2012.12.101
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-Bromosuccinimide; silver nitrate / acetone / 2 h / 20 °C / Inert atmosphere
2.1: potassium phosphate; copper(II) sulphate hydrate; 1,10-Phenanthroline / toluene / 15 h / 80 °C / Inert atmosphere
3.1: trimethylsilyl iodide / dichloromethane / 0.33 h / -78 °C / Inert atmosphere
3.2: 1 h / -78 - 0 °C / Inert atmosphere
With
potassium phosphate; N-Bromosuccinimide; 1,10-Phenanthroline; copper(II) sulphate hydrate; trimethylsilyl iodide; silver nitrate;
In
dichloromethane; acetone; toluene;
DOI:10.1016/j.tetlet.2012.12.101
