(E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one

Base Information

• Chemical Name: (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one
• CAS No.: 1255948-99-2
• Molecular Formula: C₁₃H₁₅N₅OS
• Molecular Weight: 289.361
• Mol file: 1255948-99-2.mol

Synonyms:(E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one

Chemical Property of (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one

There total 5 articles about (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

5,7-dimethyl-3-thioxoperhydroimidazo[4,5-e][1,2,4]triazin-6-one + benzaldehyde (100-52-7) → (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one (1255948-99-2) + N-{4,6-dimethyl-5-oxo-2-thioxohexahydroimidazo[4,5-d]-imidazol-1(2H)-yl}formamide

Guidance literature:

With formic acid; In acetone; at 55 ℃; for 3h; Solvent; Temperature;

DOI:10.1055/s-0036-1588388

Reference yield: 55.0%

1,3-dimethyl-4,5-bis(3-thiosemicarbazido)imidazolidin-2-one + benzaldehyde (100-52-7) → 5,7-dimethyl-3-thioxoperhydroimidazo[4,5-e][1,2,4]triazin-6-one + 1-benzylidene thiosemicarbazide (1627-73-2) + (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one (1255948-99-2)

Guidance literature:

With hydrogenchloride; In methanol; water; for 1.5h; Reflux;

DOI:10.1016/j.mencom.2010.09.016

Reference yield: 55.0%

5,7-dimethyl-3-thioxoperhydroimidazo[4,5-e][1,2,4]triazin-6-one + benzaldehyde (100-52-7) → (E)-4-(benzylideneamino)-1,3-dimethyl-5-thioxohexahydroimidazo[4,5-d]imidazol-2(1H)-one (1255948-99-2)

Guidance literature:

With hydrogenchloride; In methanol; Reflux;

DOI:10.1055/s-0032-1317194

upstream raw materials:

benzaldehyde

4,5-dihydroxy-1,3-dimethylimidazolidin-2-one