2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Base Information

Chemical Name:2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole
CAS No.:1447031-56-2
Molecular Formula:C₂₃H₁₉F₃N₂
Molecular Weight:380.412
Hs Code.:

Synonyms:2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Suppliers and Price of 2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

There total 5 articles about 2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 3042-22-6
2-phenyl-1H-pyrrole

: 1447004-23-0
1-[5-(4-methylphenyl)-1H-pyrrol-2-yl]-2,2,2-trifluoro-1-ethanol

: 1447031-56-2
2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Guidance literature:: With phosphorus pentoxide; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;
DOI:10.1002/ejoc.201300212

Reference yield:

: 2089-33-0
4-methylacethophenone oxime

: 1447031-56-2
2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Guidance literature:: Multi-step reaction with 4 steps

1: dimethyl sulfoxide / Alkaline conditions

2: pyridine / diethyl ether / 2.5 h

3: sodium hydrogencarbonate; sodium tetrahydroborate / methanol / 0.67 h

4: phosphorus pentoxide / dichloromethane / 16 h / 20 °C / Inert atmosphere

With pyridine; sodium tetrahydroborate; phosphorus pentoxide; sodium hydrogencarbonate; In methanol; diethyl ether; dichloromethane; dimethyl sulfoxide;
DOI:10.1002/ejoc.201300212

Reference yield:

: 113768-63-1
2,2,2-Trifluoro-1-(5-p-tolyl-1H-pyrrol-2-yl)-ethanone

: 1447031-56-2
2-(4-methylphenyl)-5-[2,2,2-trifluoro-1-(5-phenyl-1H-pyrrol-2-yl)-ethyl]-1H-pyrrole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydrogencarbonate; sodium tetrahydroborate / methanol / 0.67 h

2: phosphorus pentoxide / dichloromethane / 16 h / 20 °C / Inert atmosphere

With sodium tetrahydroborate; phosphorus pentoxide; sodium hydrogencarbonate; In methanol; dichloromethane;
DOI:10.1002/ejoc.201300212