1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

Base Information

Chemical Name:1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine
CAS No.:952016-31-8
Molecular Formula:C₁₇H₃₀BrNO₂Si₂
Molecular Weight:416.506
Hs Code.:

Synonyms:1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

Suppliers and Price of 1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

There total 1 articles about 1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 13528-93-3
1,2-bis-(chlorodimethylsilyl)ethane

: 64638-07-9
4-bromo-2,5-dimethoxyphenylisopropylamine

: 952016-31-8
1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 2h;
DOI:10.1016/S0040-4039(00)82391-6

Reference yield:

: 952016-31-8
1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

: 121649-01-2
4-(2-Fluoroethyl)-2,5-dimethoxyamphetamine

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) t-butyllithium, 3.) 10percent KOH / 1.) ether, -78 deg C, 15 min, 2.) ether, -78 deg C, 1 h, hexane, reflux 3 h, 3.) CH₃OH, reflux 4 h

2: 89 percent / Et₃N / diethyl ether / 1 h / 0 - 35 °C

3: 96 percent / pyridine / 12 h / 0 °C

4: 55 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / Heating

5: 86 percent / KOH / H₂O; propan-2-ol / 0.5 h / 45 °C

With pyridine; potassium hydroxide; tetrabutyl ammonium fluoride; tert.-butyl lithium; triethylamine; In tetrahydrofuran; diethyl ether; water; isopropyl alcohol;
DOI:10.1016/S0040-4039(00)82391-6

Reference yield:

: 952016-31-8
1-[2-(4-Bromo-2,5-dimethoxy-phenyl)-1-methyl-ethyl]-2,2,5,5-tetramethyl-[1,2,5]azadisilolidine

: 121649-08-9
(+/-)-1-<2,5-Dimethoxy-4-(ethen)phenyl>-2-trifluoroacetamidopropane

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) t-butyllithium, 3.) 10percent KOH / 1.) ether, -78 deg C, 15 min, 2.) ether, -78 deg C, 1 h, hexane, reflux 3 h, 3.) CH₃OH, reflux 4 h

2: 89 percent / Et₃N / diethyl ether / 1 h / 0 - 35 °C

3: 96 percent / pyridine / 12 h / 0 °C

4: 18 percent / tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / Heating

With pyridine; potassium hydroxide; tetrabutyl ammonium fluoride; tert.-butyl lithium; triethylamine; In tetrahydrofuran; diethyl ether;
DOI:10.1016/S0040-4039(00)82391-6