7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone

Base Information

• Chemical Name: 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone
• CAS No.: 82448-70-2
• Molecular Formula: C₂₇H₂₂O₇
• Molecular Weight: 458.467
• Mol file: 82448-70-2.mol

Synonyms:7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone

Chemical Property of 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone

There total 9 articles about 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

2-methyl-3-buten-2-ol (115-18-4) + 7-benzoyloxy-2',4',5-trihydroxyisoflavone (82448-69-9) → 7-benzoyloxy-2',4',5-trihydroxy-5'-(3-methyl-2-butenyl)isoflavone (82448-71-3) + 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone (82448-70-2) + 7-benzoyloxy-2',4',5-trihydroxy-3',5'-bis(3-methyl-2-butenyl)isoflavone (96909-31-8)

Guidance literature:

With boron trifluoride diethyl etherate; In 1,4-dioxane; at 51 - 53 ℃; for 6h;

DOI:10.1246/bcsj.58.136

Reference yield: 18.0%

2-methyl-3-buten-2-ol (115-18-4) + 7-benzoyloxy-2',4',5-trihydroxyisoflavone (82448-69-9) → 7-benzoyloxy-2',4',5-trihydroxy-5'-(3-methyl-2-butenyl)isoflavone (82448-71-3) + 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone (82448-70-2)

Guidance literature:

DOI:10.1246/cl.1982.675

Reference yield:

2'-acetoxy-2,4,4',6'-tetrakis(benzyloxy)chalcone (82448-62-2) → 7-benzoyloxy-2',4',5-trihydroxy-3'-(3-methyl-2-butenyl)isoflavone (82448-70-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 79 percent / 1) thallium (III)nitrate trihydrate; 2) 10percent hydrochloric acid; / methanol / 1) 32-35 deg C; 8 h; 2) reflux; 3 h;

2: 97 percent / hydrogenolyse / 10percent Pd-C / methanol

3: 37 percent / pyridine / diethyl ether / 5.5 h / 2 - 5 °C

4: 18 percent / BF₃-etherate / dioxane / 6 h / 51 - 53 °C

With pyridine; hydrogenchloride; hydrogenolyse; boron trifluoride diethyl etherate; thallium(III) nitrate; palladium on activated charcoal; In 1,4-dioxane; methanol; diethyl ether;

DOI:10.1246/bcsj.58.136

upstream raw materials:

2-methyl-3-buten-2-ol

7-benzoyloxy-2',4',5-trihydroxyisoflavone

1-[2,4-bis(benzyloxy)-6-hydroxyphenyl]ethanone

2',4',5,7-tetrahydroxyisoflavone

Downstream raw materials:

2',4',5,7-tetraacetoxy-3'-(3-methyl-2-butenyl)isoflavone

licoisoflavone A