1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane

Base Information

• Chemical Name: 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane
• CAS No.: 1426304-22-4
• Molecular Formula: C₂₀H₂₁N₃O₃
• Molecular Weight: 351.405
• Mol file: 1426304-22-4.mol

Synonyms:1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane

Chemical Property of 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane

Chemical Property:

Purity/Quality:

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Technology Process of 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane

There total 2 articles about 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

ethyl 3-bromo-2-(hydroxyimino)propanoate (73472-94-3) + 5-phenyldipyrromethane (107798-98-1) → 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane (1426304-22-4)

Guidance literature:

With sodium carbonate; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.tetlet.2013.01.032

Reference yield:

ethyl Bromopyruvate (70-23-5) → 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane (1426304-22-4)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine

2: sodium carbonate / dichloromethane / 24 h / 20 °C

With hydroxylamine; sodium carbonate; In dichloromethane;

DOI:10.1016/j.tetlet.2013.01.032

Reference yield: 34.0%

ethyl 3-bromo-2-(hydroxyimino)propanoate (73472-94-3) + 1-(2'-ethoxycarbonyl-2'-hydroxyiminoethyl)-5-phenyldipyrromethane (1426304-22-4) → 1,9-bis(2'-ethoxycarbonyl-2’-hydroxyiminoethyl)-5-phenyldipyrromethane (1426304-30-4)

Guidance literature:

With sodium carbonate; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1016/j.tetlet.2013.01.032

upstream raw materials:

ethyl 3-bromo-2-(hydroxyimino)propanoate

5-phenyldipyrromethane

ethyl Bromopyruvate

Downstream raw materials:

1,9-bis(2'-ethoxycarbonyl-2’-hydroxyiminoethyl)-5-phenyldipyrromethane