optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-⁽¹⁾

Base Information

• Chemical Name: optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-⁽¹⁾
• CAS No.: 101869-71-0
• Molecular Formula: C₈H₁₆O₂
• Molecular Weight: 144.214
• Mol file: 101869-71-0.mol

Synonyms:optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-⁽¹⁾

Chemical Property of optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-⁽¹⁾

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-⁽¹⁾

There total 18 articles about optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-⁽¹⁾ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

5-methyl-1-oxaspiro[2.5]octane (90112-44-0) → (3S,5S)-5-methyl-1-oxaspiro[2.5]octane (864158-73-6) + (1R,3R)-1-hydroxy-3-methyl-cyclohexanemethanol + (1S,3S)-1-hydroxy-3-methyl-cyclohexanemethanol (101869-71-0)

Guidance literature:

With potassium phosphate buffer; Rhodotorula glutinis ATCC 201718 hydrolase; at 35 ℃; for 6h; pH=8.0;

DOI:10.1021/jo050533w

Reference yield:

→ optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-(1) (101869-71-0) + 3-Methylcyclohexanone (591-24-2,625-96-7)

Guidance literature:

With potassium permanganate;

Reference yield:

1-methyl-3-methylene-cyclohexane (3101-50-6) → optically inactive 3-methyl-1-hydroxymethyl-cyclohexanol-(1) (101869-71-0) + 3-Methylcyclohexanone (591-24-2,625-96-7)

Guidance literature:

upstream raw materials:

5-methyl-1-oxaspiro[2.5]octane

(3S,5S)-5-methyl-1-oxaspiro[2.5]octane

ethyl N-methyl-N-nitrosocarbamate

3-Methylcyclohexanone

Downstream raw materials:

cis/trans-3-Methyl-1-cyclohexancarbaldehyd

cis-1,3-dimethylcyclohexanol

cis-1,3-Dimethylcyclohexan-1-ol