methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

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Chemical Name:methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate
CAS No.:1261531-24-1
Molecular Formula:C₂₀H₂₀FN₃O₃
Molecular Weight:369.396
Hs Code.:

Synonyms:methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

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Chemical Property of methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

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Technology Process of methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

There total 1 articles about methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 932396-34-4
1-(4-fluorobenzyl)-5-(methoxycarbonyl)-1H-pyrrolo[2,3-c]pyridine-3-carboxylic acid

: 75-31-0
isopropylamine

: 1261531-24-1
methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

Guidance literature:: 1-(4-fluorobenzyl)-5-(methoxycarbonyl)-1H-pyrrolo[2,3-c]pyridine-3-carboxylic acid; With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

isopropylamine; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2010.10.022

Reference yield: 62.0%

: 1261531-24-1
methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate

: 4229-44-1
N-methylhydroxyamine hydrochloride

: 1-(4-fluorobenzyl)-N₅-hydroxy-N₃-isopropyl-N₅-methyl-1H-pyrrolo[2,3-c]pyridine-3,5-dicarboxamide

Guidance literature:: N-methylhydroxyamine hydrochloride; With sodium tert-pentoxide; In 1-methyl-pyrrolidin-2-one; at 0 ℃; Inert atmosphere;

methyl 1-(4-fluorobenzyl)-3-(isopropylcarbamoyl)-1H-pyrrolo[2,3-c]pyridine-5-carboxylate; In 1-methyl-pyrrolidin-2-one; at 0 ℃; Inert atmosphere;
DOI:10.1016/j.bmcl.2010.10.022