Hydroxy(methyl)azanium;chloride

Base Information

• Chemical Name: Hydroxy(methyl)azanium;chloride
• CAS No.: 4229-44-1
• Molecular Formula: CH6ClNO
• Molecular Weight: 83.5177
• Hs Code.: 29280090
• Mol file: 4229-44-1.mol

Synonyms:hydroxy(methyl)azanium;chloride;N-Hydroxy-N-methylammonium chloride;AKOS037656257;7G-957

Chemical Property of Hydroxy(methyl)azanium;chloride

Chemical Property:

• Appearance/Colour: White to almost white crystals or cryst. powder
• Vapor Pressure: 96.6mmHg at 25°C
• Melting Point: 86-88 °C(lit.)
• Boiling Point: 69.4 °C at 760 mmHg
• Flash Point: 41.9 °C
• PSA: 32.26000
• Density: 1.36 g/cm3
• LogP: 0.78790
• Storage Temp.: Inert atmosphere,Room Temperature
• Sensitive.: Hygroscopic
• Solubility.: H2O: 0.1 g/mL, clear, very faintly yellow
• Water Solubility.: soluble
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 83.0137915
• Heavy Atom Count: 4
• Complexity: 4.8

Purity/Quality:

97% ^*data from raw suppliers

N-Methylhydroxylamine HCl ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[NH2+]O.[Cl-]
• Uses: N-Methylhydroxylamine is used as an inorganic catalyst used in the transamidation of primary amides with amines. N-Methylhydroxylamine hydrochloride is used as an inorganic catalyst used in the transamidation of primary amides with amines. It is employed in constructing hydroxamates, important functional groups for the complexation of iron.

Technology Process of Hydroxy(methyl)azanium;chloride

There total 10 articles about Hydroxy(methyl)azanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

C-(2-nitrophenyl)-N-methyl-nitrone (41106-02-9) → N-methylhydroxyamine hydrochloride (4229-44-1) + 2-nitrobenzaldehyde oxime (3717-25-7,4836-00-4,6635-41-2)

Guidance literature:

With hydroxylamine hydrochloride; In methanol; diethyl ether; at 20 ℃; for 4h;

DOI:10.1080/00397910500191169

Reference yield: 94.0%

4-(N-methylnitrono)-2,2,5,5-tetramethyltetrahydrofuran-3-one E-isomer (67036-74-2,67036-80-0) → 2,2,5,5-Tetramethyl-furan-3,4-dione (14744-18-4) + N-methylhydroxyamine hydrochloride (4229-44-1)

Guidance literature:

With hydrogenchloride; Heating;

Reference yield:

N,O-Dimesyl-N-methylhydroxylamin (80653-57-2) → 1,3,5-Trioxan (110-88-3) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-Methylhydroxylamine (593-77-1) + N-methylhydroxyamine hydrochloride (4229-44-1) + methanesulfonic acid sodium salt (2386-57-4)

Guidance literature:

With sodium hydroxide; In water; Mechanism; Product distribution; hydrolysis with basic, neutral and acidic aqu. solutions;

upstream raw materials:

nitromethane

4-(N-methylnitrono)-2,2,5,5-tetramethyltetrahydrofuran-3-one E-isomer

hydrogenchloride

N-methyl-diphenyl-nitrone

Downstream raw materials:

(methyl-oxy-imino)-malonic acid di-p-toluidide

(Z)-N-(1-phenylethylidene)methanamine N-oxide

N-methyl-diphenyl-nitrone

2,3-dimethoxy-6-[(methyl-oxy-imino)-methyl]-benzoic acid