C₂₉H₃₃F₆NO₄S

Base Information

• Chemical Name: C₂₉H₃₃F₆NO₄S
• CAS No.: 1257126-91-2
• Molecular Formula: C₂₉H₃₃F₆NO₄S
• Molecular Weight: 605.642
• Mol file: 1257126-91-2.mol

Synonyms:C₂₉H₃₃F₆NO₄S

Chemical Property of C₂₉H₃₃F₆NO₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₂₉H₃₃F₆NO₄S

There total 4 articles about C₂₉H₃₃F₆NO₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

C31H37F6NO4S → C29H33F6NO4S (1257126-91-2)

Guidance literature:

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 40 - 45 ℃; for 2h; Inert atmosphere;

Reference yield:

C22H23F6NO2S → C29H33F6NO4S (1257126-91-2)

Guidance literature:

Multi-step reaction with 3 steps

1.1: diethyl ether; dichloromethane / 3 h / -78 °C

2.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h / 0 °C / Inert atmosphere

2.2: 18 h / 23 °C / Inert atmosphere

3.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / 40 - 45 °C / Inert atmosphere

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; sodium hydride; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; mineral oil;

Reference yield:

2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethanone (530441-99-7) → C29H33F6NO4S (1257126-91-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: titanium(IV) isopropylate / 36 h / 23 °C / Inert atmosphere

2.1: diethyl ether; dichloromethane / 3 h / -78 °C

3.1: sodium hydride / mineral oil; N,N-dimethyl-formamide / 1 h / 0 °C / Inert atmosphere

3.2: 18 h / 23 °C / Inert atmosphere

4.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 2 h / 40 - 45 °C / Inert atmosphere

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; titanium(IV) isopropylate; sodium hydride; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; mineral oil;

upstream raw materials:

2-[(R)-1-(3,5-Bis-trifluoromethyl-phenyl)-ethoxy]-1-phenyl-ethanone