2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate

Base Information

• Chemical Name: 2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate
• CAS No.: 1426231-09-5
• Molecular Formula: C₁₅H₁₄F₃NO₃
• Molecular Weight: 313.276
• Mol file: 1426231-09-5.mol

Synonyms:2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate

Chemical Property of 2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate

There total 1 articles about 2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

N-phenyl-N-pivaloylglycine (166033-86-9) + trifluoroacetic anhydride (407-25-0) → 2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate (1426231-09-5)

Guidance literature:

In ethyl acetate; at 0 ℃; for 3h;

DOI:10.1039/c6cc01627h

Reference yield: 97.0%

2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate (1426231-09-5) → 3-tert-butyl-6-trifluoromethyl-5,6-dihydro-4-phenyl-4H-1,2,4-oxadiazin-6-ol (1426231-12-0)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In N,N-dimethyl-formamide; at 0 - 80 ℃; for 3h; regiospecific reaction; Inert atmosphere;

DOI:10.3987/COM-12-12627

Reference yield: 95.0%

n-butylphosphine (1732-74-7) + 2-tert-butyl-4-trifluoroacetyl-3-phenyl-1,3-oxazol-3-ium-5-olate (1426231-09-5) → C27H41F3NO3P

Guidance literature:

In tetrahydrofuran; at 20 ℃; for 5h; Inert atmosphere;

DOI:10.1039/c6cc01627h

upstream raw materials:

N-phenyl-N-pivaloylglycine

trifluoroacetic anhydride

Downstream raw materials:

3-tert-butyl-6-trifluoromethyl-5,6-dihydro-4-phenyl-4H-1,2,4-oxadiazin-6-ol