7-benzyldiosmetin

Base Information

• Chemical Name: 7-benzyldiosmetin
• CAS No.: 159355-57-4
• Molecular Formula: C₂₃H₁₈O₆
• Molecular Weight: 390.392
• Mol file: 159355-57-4.mol

Synonyms:7-benzyldiosmetin

Chemical Property of 7-benzyldiosmetin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-benzyldiosmetin

There total 2 articles about 7-benzyldiosmetin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

diosmetin (520-34-3) + benzyl chloride (100-44-7) → 7-benzyloxy-2-(3-benzyloxy-4-methoxyphenyl)-5-hydroxy-4H-chromen-4-one (172805-73-1) + 7-benzyldiosmetin (159355-57-4)

Guidance literature:

With potassium hydrogencarbonate; In N,N-dimethyl-formamide; at 120 ℃; for 2.5h;

DOI:10.1021/np040079b

Reference yield: 66.0%

diosmetin (520-34-3) + benzyl chloride (100-44-7) → 7-benzyldiosmetin (159355-57-4)

Guidance literature:

With potassium hydrogencarbonate; In N,N-dimethyl-formamide; at 120 ℃; for 2h;

DOI:10.1016/j.tetlet.2009.12.062

Reference yield: 93.0%

p-toluenesulfonyl chloride (98-59-9) + 7-benzyldiosmetin (159355-57-4) → C30H24O8S (1217077-59-2)

Guidance literature:

With pyridine; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2009.12.062

upstream raw materials:

diosmetin

benzyl chloride

Downstream raw materials:

7-benzyl-3'-phenyltetrazolyldiosmetin

7,4'-dimethoxy-5-hydroxy-6-iodoflavone

5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Refernces

• 1、 Quintin, Jerome,Lewin, Guy. "Semisynthesis of linarin, acacetin, and 6-iodoapigenin derivatives from diosmin". . p. 1624 - 1627. Retrieved 2007/10/03.