1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Base Information

Chemical Name:1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine
CAS No.:1352721-77-7
Molecular Formula:C₂₅H₂₄ClFN₆O₂
Molecular Weight:494.956
Hs Code.:

Synonyms:1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Suppliers and Price of 1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

There total 4 articles about 1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

: 19346-45-3
2-fluoro-3-nitro-6-methylpyridine

: 1352721-40-4
1-(2-chloro-benzyl)-5-fluoro-3-piperidin-4-yl-1,3-dihydro-benzoimidazol-2-ylideneamine

: 1352721-77-7
1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Guidance literature:: With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

Reference yield:

: 611-17-6
1-bromomethyl-2-chlorobenzene

: 1352721-77-7
1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium iodide / acetonitrile / 0.5 h / 20 °C

2: trifluoroacetic acid / dichloromethane; water / 1 h / 20 °C

3: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

With caesium carbonate; trifluoroacetic acid; potassium iodide; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 1352721-39-1
4-(2-amino-6-fluoro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid

: 1352721-77-7
1-(2-chloro-benzyl)-5-fluoro-3-(6'-methyl-3'-nitro-3,4,5,6-tetrahydro-2H-[1,2']bipyridinyl-4-yl)-1,3-dihydro-benzoimidazol-2-ylideneamine

Guidance literature:: Multi-step reaction with 3 steps

1: potassium iodide / acetonitrile / 0.5 h / 20 °C

2: trifluoroacetic acid / dichloromethane; water / 1 h / 20 °C

3: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C

With caesium carbonate; trifluoroacetic acid; potassium iodide; In dichloromethane; water; N,N-dimethyl-formamide; acetonitrile;