N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

Base Information

Chemical Name:N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide
CAS No.:872690-15-8
Molecular Formula:C₃₁H₂₅N₅O₄
Molecular Weight:531.571
Hs Code.:

<i>N</i>-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

Synonyms:N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

Chemical Property:

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Technology Process of N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

There total 3 articles about N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 95-14-7,27556-51-0
1,2,3-Benzotriazole

: 56876-11-0
α-Phthalimido-β-(3-methoxyphenyl)-propionamid

: 100-52-7
benzaldehyde

: 872690-15-8
N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

Guidance literature:: With toluene-4-sulfonic acid; In benzene; Heating;
DOI:10.1055/s-2005-918946

Reference yield:

: 2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionyl chloride

: 872690-15-8
N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NH₃

2: 100 percent / p-TsOH / benzene / Heating

With ammonium hydroxide; toluene-4-sulfonic acid; In benzene;
DOI:10.1055/s-2005-918946

Reference yield:

: 56876-08-5
α-Phthalimido-β-(3-methoxyphenyl)-propionsaeure

: 872690-15-8
N-(benzotriazol-1-yl-phenyl-methyl)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3-(3-methoxy-phenyl)-propionamide

Guidance literature:: Multi-step reaction with 3 steps

1: α,α-dichloromethyl methyl ether

2: aq. NH₃

3: 100 percent / p-TsOH / benzene / Heating

With ammonium hydroxide; Dichloromethyl methyl ether; toluene-4-sulfonic acid; In benzene;
DOI:10.1055/s-2005-918946