(R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Base Information

Chemical Name:(R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate
CAS No.:1357575-51-9
Molecular Formula:C₂₉H₄₅F₃N₃O₈PS₃
Molecular Weight:747.859
Hs Code.:

Synonyms:(R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Suppliers and Price of (R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

There total 7 articles about (R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 1357575-50-8
di-tert-butyl 2-(ethylamino)ethyl phosphate

: 1357575-44-0
(R)-4-((4-oxo-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide

: 1357575-51-9
(R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Guidance literature:: di-tert-butyl 2-(ethylamino)ethyl phosphate; (R)-4-((4-oxo-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide; In 1,2-dichloro-ethane; at 18 - 25 ℃; for 0.25h;

With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 18 - 25 ℃; for 4h;

Reference yield:

: 1357575-46-2
Benzyl 2-(di-tert-butoxyphosphoryloxy)ethyl(ethyl)carbamate

: 1357575-51-9
(R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrogen / 5%-palladium/activated carbon / methanol / 18 - 25 °C

2.1: 1,2-dichloro-ethane / 0.25 h / 18 - 25 °C

2.2: 4 h / 18 - 25 °C

With hydrogen; 5%-palladium/activated carbon; In methanol; 1,2-dichloro-ethane;

Reference yield:

: 1027345-08-9
4-fluoro-3-[(trifluoromethyl)sulfonyl]benzenesulfonamide

: 1357575-51-9
(R)-di-tert-butyl 2-(ethyl(4-(phenylthio)-3-(4-sulfamoyl-2-(trifluoromethylsulfonyl)phenylamino)butyl)amino)ethyl phosphate

Guidance literature:: Multi-step reaction with 3 steps

1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 1.5 h / 50 °C

2.1: diisobutylaluminium hydride / dichloromethane; n-heptane / 3 h / -78 °C

2.2: -78 - 25 °C

3.1: 1,2-dichloro-ethane / 0.25 h / 18 - 25 °C

3.2: 4 h / 18 - 25 °C

With diisobutylaluminium hydride; N-ethyl-N,N-diisopropylamine; In n-heptane; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;