N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin

Base Information

• Chemical Name: N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin
• CAS No.: 145594-15-6
• Molecular Formula: C₄₈H₄₄N₄O₁₂
• Molecular Weight: 868.897

Synonyms:N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin

Chemical Property of N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin

There total 5 articles about N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) + Succinic acid mono-{(2R,3S,6R)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-pyran-3-yl} ester (145610-84-0) → N4-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin (145594-15-6)

Guidance literature:

With pyridine; dicyclohexyl-carbodiimide; In 1,4-dioxane; for 3h; Ambient temperature;

DOI:10.1002/hlca.19920750503

Reference yield:

4,4'-dimethoxytrityl chloride (40615-36-9) → N4-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin (145594-15-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / pyridine / (Bu₄N)ClO₄ / 1 h / Ambient temperature

2: 70 percent / 4-(dimethylamino)pyridine, pyridine / 20 h / Ambient temperature

3: 96 percent / pyridine, N,N'-dicyclohexylcarbodiimide / dioxane / 3 h / Ambient temperature

With pyridine; dmap; dicyclohexyl-carbodiimide; tetrabutylammonium perchlorate; In 1,4-dioxane;

DOI:10.1002/hlca.19920750503

Reference yield:

N4-Benzoyl-1-(2',3'-dideoxy-β-D-glucopyranosyl)cytosin (145593-86-8) → N4-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin (145594-15-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 88 percent / pyridine / (Bu₄N)ClO₄ / 1 h / Ambient temperature

2: 70 percent / 4-(dimethylamino)pyridine, pyridine / 20 h / Ambient temperature

3: 96 percent / pyridine, N,N'-dicyclohexylcarbodiimide / dioxane / 3 h / Ambient temperature

With pyridine; dmap; dicyclohexyl-carbodiimide; tetrabutylammonium perchlorate; In 1,4-dioxane;

DOI:10.1002/hlca.19920750503

upstream raw materials:

4-nitro-phenol

Succinic acid mono-{(2R,3S,6R)-6-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-tetrahydro-pyran-3-yl} ester

4,4'-dimethoxytrityl chloride

N⁴-Benzoyl-1-(2',3'-dideoxy-β-D-glucopyranosyl)cytosin

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 145594-15-6 N⁴-Benzoyl-1-<2',3'-dideoxy-6'-O-<(4,4'-dimethoxytriphenyl)methyl>-4'-O-<4-O-(4-nitrophenyl)succinyl>-β-D-glucopyranosyl>cytosin

Send

Send

Metric Ton KG G Pound L ML

Send

Send