N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide

Base Information

• Chemical Name: N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide
• CAS No.: 551944-30-0
• Molecular Formula: C₃₇H₄₃NO₃
• Molecular Weight: 549.753
• Mol file: 551944-30-0.mol

Synonyms:N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide

Chemical Property of N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide

There total 2 articles about N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1S,4aS,10aR)-6-(benzyloxy)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxamide (551944-28-6) + 1-phenylcyclohexylcarbonyl chloride (2890-42-8) → N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide (551944-30-0)

Guidance literature:

(1S,4aS,10aR)-6-(benzyloxy)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxamide; With sodium hexamethyldisilazane; In tetrahydrofuran;

1-phenylcyclohexylcarbonyl chloride; In tetrahydrofuran;

DOI:10.1016/j.bmcl.2005.06.100

Reference yield:

→ N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide (551944-30-0)

Guidance literature:

Reference yield:

N-[(4β,5α)-12-(Benzyloxy)-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide (551944-30-0) → N-[(4β,5α)-12-Hydroxy-16-oxopodocarpa-8,11,13-trien-16-yl]-1-phenylcyclohexanecarboxamide

Guidance literature:

With hydrogen; palladium on activated charcoal; under 2327.17 Torr;

DOI:10.1016/j.bmcl.2005.06.100

upstream raw materials:

(1S,4aS,10aR)-6-(benzyloxy)-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthrene-1-carboxamide

1-phenylcyclohexylcarbonyl chloride