2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide

Base Information

• Chemical Name: 2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide
• CAS No.: 175659-55-9
• Molecular Formula: C₁₇H₁₉N₅OS₂
• Molecular Weight: 373.503
• Mol file: 175659-55-9.mol

Synonyms:2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide

Chemical Property of 2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of 2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide

There total 2 articles about 2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

1-phenylpyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dithione (6289-02-7) + 2-bromohexanamide (13161-97-2) → 2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide (175659-55-9)

Guidance literature:

With pyridine; for 2h; Ambient temperature;

DOI:10.1021/jm960052s

Reference yield: 80.0%

2-bromohexanamide (13161-97-2) + 1-phenyl-5H,7H-pyrazolo<3,4-d>pyrimidine-4,6-dithione (6289-02-7) → 2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide (175659-55-9)

Guidance literature:

With pyridine; for 2h; Ambient temperature;

DOI:10.1016/0960-894X(96)00027-3

Reference yield: 59.0%

2-(4-Mercapto-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide (175659-55-9) + methyl iodide (74-88-4) → 2-(4-Methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide (175659-54-8)

Guidance literature:

With sodium hydroxide; for 1h; Ambient temperature;

DOI:10.1021/jm960052s

upstream raw materials:

1-phenylpyrazolo<3,4-d>pyrimidine-4,6(5H,7H)-dithione

2-bromohexanamide

1-phenyl-5H,7H-pyrazolo<3,4-d>pyrimidine-4,6-dithione

Downstream raw materials:

2-(4-Methylsulfanyl-1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylsulfanyl)-hexanoic acid amide