1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

Base Information

Chemical Name:1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester
CAS No.:99522-55-1
Molecular Formula:C₂₂H₂₈N₄O₆
Molecular Weight:444.488
Hs Code.:

Synonyms:1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

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Chemical Property of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

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Technology Process of 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

There total 1 articles about 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 110-85-0
piperazine

: 54527-89-8
2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(2-chloroethyl)ester-5-methyl ester

: 99522-55-1
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

Guidance literature:: In acetonitrile; for 3h; Reflux;

Reference yield: 71.0%

: 99522-55-1
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

: 90943-48-9
1-(3-chloropropoxy)-2-methoxybenzene

: 1042712-01-5
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-4-(3-(2-methoxyphenoxy)propyl)piperazinyl)ethyl ester

Guidance literature:: With sodium hydroxide; In toluene; for 2h; Reflux;

Reference yield: 56.3%

: 99522-55-1
1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester

: 2210-74-4
2-(2-methoxy-phenoxymethyl)-oxirane

: 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-4-(3-(2-methoxyphenoxy)-2-hydroxpropyl)piperazinyl)ethyl ester hydrochloride

Guidance literature:: 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinecarboxylic acid methyl ester 2-(N-1-piperazinyl)ethyl ester; 2-(2-methoxy-phenoxymethyl)-oxirane; With triethylamine; In acetonitrile; at 60 ℃; for 1h;

With hydrogenchloride; In diethyl ether; at 20 ℃; pH=2;