(+/-)-Muscarine chloride

Base Information

Chemical Name:(+/-)-Muscarine chloride
CAS No.:2936-25-6
Molecular Formula:C₉H₂₀NO₂*Cl
Molecular Weight:209.716
Hs Code.:
European Community (EC) Number:636-708-7
ChEMBL ID:CHEMBL1871893
DSSTox Substance ID:DTXSID701018053
Mol file:2936-25-6.mol

Synonyms:(+/-)-Muscarine chloride;(+/-)-Muscarine chloride hydrate;2936-25-6;(4-hydroxy-5-methyloxolan-2-yl)methyl-trimethylazanium;chloride;ribo-Hexitol, 2,5-anhydro-1,3,6-trideoxy-1-(trimethylammonio)-, chloride;MLS002153170;CHEMBL1871893;DTXSID701018053;HMS2235F18;HMS3372G09;MFCD00055067;AKOS030241231;Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate;SMR001230663;(+/-)-Muscarine chloride hydrate, >=98% (HPLC);J-017483;Trimethyl(tetrahydro-4-hydroxy-5-methylfurfuryl)ammonium chloride;93457-82-0

Suppliers and Price of (+/-)-Muscarine chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+/-)-MuscarineChloride
25mg
$ 1175.00

Sigma-Aldrich
(±)-Muscarine chloride hydrate ≥98% (HPLC)
25mg
$ 562.00

Sigma-Aldrich
(±)-Muscarine chloride hydrate ≥98% (HPLC)
5mg
$ 140.00

American Custom Chemicals Corporation
(+/-)-MUSCARINE CHLORIDE 95.00%
10MG
$ 883.49

American Custom Chemicals Corporation
(+/-)-MUSCARINE CHLORIDE 95.00%
5MG
$ 578.00

Total 10 raw suppliers

Chemical Property of (+/-)-Muscarine chloride

Chemical Property:

Melting Point:180-181oC
Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：29.46000
Density:g/cm³
LogP:-2.76510
Storage Temp.:room temp
Solubility.:deionized water: ≥20mg/mL
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:209.1182566
Heavy Atom Count:13
Complexity:153

Purity/Quality:

98%,99%, ^*data from raw suppliers

(+/-)-MuscarineChloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22-36
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1C(CC(O1)C[N+](C)(C)C)O.[Cl-]
Description Muscarine is a natural alkaloid that is found in a number of wild mushrooms. Despite the fact that muscarine does not have any therapeutic value, it is of interest because of its expressed toxic properties, which made it one of the first systematically studied cholinomimetic substances. (+/-)-MUSCARINE CHLORIDE was an underlying classification of cholinergic muscarinic receptors. The action of muscarine is similar to that of acetylcholine on peripheral autonomic effector organs, and atropine is an antagonist to it. Unlike acetylcholine, muscarine does not act on nicotinic receptors.
Uses (+/-)-Muscarine Chloride is a muscarinic acteylcholine receptor agonist.

Technology Process of (+/-)-Muscarine chloride

There total 20 articles about (+/-)-Muscarine chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 116246-31-2
(2S,3R,5S)-5-Aminomethyl-2-methyl-tetrahydro-furan-3-ol

: 74-88-4
methyl iodide

: 2303-35-7,2936-25-6,2936-26-7,35119-35-8,35119-39-2,35119-40-5,55086-63-0,74311-04-9,93457-82-0,93507-32-5,93507-33-6
(+/-)-Muscarine chloride

Guidance literature:: With 1,2,2,6,6-pentamethylpiperidine; In ethyl acetate;
DOI:10.1016/S0040-4039(00)80041-6

Reference yield:

: 74282-54-5
(3R,5S,6S)-3,5-Bis-benzyloxymethoxy-6-methyl-tetrahydro-pyran-2-ol

: 2303-35-7,2936-25-6,2936-26-7,35119-35-8,35119-39-2,35119-40-5,55086-63-0,74311-04-9,93457-82-0,93507-32-5,93507-33-6
(+/-)-Muscarine chloride

Guidance literature:: Multi-step reaction with 7 steps

1: 90 percent / CrO₃*2C₅H₅N / CH₂Cl₂

2: 97 percent / benzene / 3 h / 25 °C

3: 93 percent / Et₃N / CH₂Cl₂

4: 81 percent / H₂ / 10percent Pd/C / various solvent(s)

5: LiAlH₄ / diethyl ether / 1 h / Heating

7: AgCl / H₂O

With lithium aluminium tetrahydride; hydrogen; dipyridine chromium trioxide; triethylamine; silver(I) chloride; palladium on activated charcoal; In diethyl ether; dichloromethane; water; benzene;
DOI:10.1021/jo01304a056

Reference yield:

: 74282-55-6,74298-00-3
(3S,5R,6R)-3,5-Bis-benzyloxymethoxy-6-methyl-tetrahydro-pyran-2-one

: 2303-35-7,2936-25-6,2936-26-7,35119-35-8,35119-39-2,35119-40-5,55086-63-0,74311-04-9,93457-82-0,93507-32-5,93507-33-6
(+/-)-Muscarine chloride

Guidance literature:: Multi-step reaction with 6 steps

1: 97 percent / benzene / 3 h / 25 °C

2: 93 percent / Et₃N / CH₂Cl₂

3: 81 percent / H₂ / 10percent Pd/C / various solvent(s)

4: LiAlH₄ / diethyl ether / 1 h / Heating

6: AgCl / H₂O

With lithium aluminium tetrahydride; hydrogen; triethylamine; silver(I) chloride; palladium on activated charcoal; In diethyl ether; dichloromethane; water; benzene;
DOI:10.1021/jo01304a056