4-Iodoacetamidosalicylic acid

Base Information

• Chemical Name: 4-Iodoacetamidosalicylic acid
• CAS No.: 4323-00-6
• Molecular Formula: C9H8INO4
• Molecular Weight: 321.0686
• Hs Code.: 2924299090
• European Community (EC) Number: 636-957-1
• NSC Number: 55320
• UNII: DUH6NQ2YPW
• DSSTox Substance ID: DTXSID30195796
• Nikkaji Number: J54.310A
• Wikidata: Q83068859
• Mol file: 4323-00-6.mol

Synonyms:4-iodoacetamidosalicylic acid

Chemical Property of 4-Iodoacetamidosalicylic acid

Chemical Property:

• Vapor Pressure: 6.76E-12mmHg at 25°C
• Boiling Point: 526.1°Cat760mmHg
• Flash Point: 272°C
• PSA: 86.63000
• Density: 2.108g/cm³
• LogP: 1.53690
• Storage Temp.: 2-8°C
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 320.94981
• Heavy Atom Count: 15
• Complexity: 259

Purity/Quality:

99% ^*data from raw suppliers

4-IODOACETAMIDOSALICYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC(=C(C=C1NC(=O)CI)O)C(=O)O

Technology Process of 4-Iodoacetamidosalicylic acid

There total 4 articles about 4-Iodoacetamidosalicylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(2-chloro-acetylamino)-2-hydroxy-benzoic acid (14463-22-0) → 4-Iodacetamidosalicylsaeure (4323-00-6)

Guidance literature:

With acetone; potassium iodide;

Reference yield:

sodium p-aminosalicylate (133-10-8) → 4-Iodacetamidosalicylsaeure (4323-00-6)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous sodium acetate

2: acetone; KI

With sodium acetate; acetone; potassium iodide;

Reference yield:

2-iodoacetyl chloride (38020-81-4) + sodium p-aminosalicylate (133-10-8) → 4-Iodacetamidosalicylsaeure (4323-00-6)

Guidance literature:

With water;

upstream raw materials:

2-iodoacetyl chloride

sodium p-aminosalicylate

4-(2-chloro-acetylamino)-2-hydroxy-benzoic acid