4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride

Base Information

• Chemical Name: 4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride
• CAS No.: 396124-33-7
• Molecular Formula: C₁₈H₁₄ClN₇O₃S
• Molecular Weight: 443.873
• Mol file: 396124-33-7.mol

Synonyms:4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride

Chemical Property of 4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride

There total 1 articles about 4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

2-furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine (160098-96-4) → 4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride (396124-33-7)

Guidance literature:

With chlorosulfonic acid; at 0 ℃; for 1h;

DOI:10.1021/jm010924c

Reference yield: 60.0%

4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride (396124-33-7) → 4-[2-(5-amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-ethyl]-benzenesulfonic acid

Guidance literature:

With aq. 10percent HCl; In 1,4-dioxane; at 20 ℃; for 48h;

DOI:10.1021/jm010924c

Reference yield:

4-[2-(5-amino-2-furan-2-ylpyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)ethyl]benzenesulfonyl chloride (396124-33-7) → 4-[2-(5-amino-2-furan-2-yl-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-7-yl)-ethyl]-benzenesulfonamide

Guidance literature:

With ammonia; In 1,4-dioxane; at 0 ℃;

DOI:10.1021/jm010924c

upstream raw materials:

2-furan-2-yl-7-phenethyl-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-ylamine