N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide

Base Information

• Chemical Name: N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide
• CAS No.: 1204740-42-0
• Molecular Formula: C₁₆H₂₀N₄O₂S
• Molecular Weight: 332.426
• Mol file: 1204740-42-0.mol

Synonyms:N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide

Chemical Property of N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide

There total 1 articles about N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

5-methoxyisatine (39755-95-8) + 4-cyclohexyl-thiosemicarbazide (21198-18-5) → N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (1204740-42-0)

Guidance literature:

With sulfuric acid; In ethanol; at 70 ℃; for 4h;

DOI:10.1016/j.ica.2019.04.019

Reference yield: 82.0%

copper(II) chloride monohydrate + N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (1204740-42-0) → bis[N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3ylidene)hydrazinecarbothioamide]

Guidance literature:

In ethanol; for 5h;

DOI:10.1016/j.ica.2019.04.019

Reference yield: 80.0%

N-cyclohexyl-2-(5-methoxy-2-oxoindolin-3-ylidene)hydrazinecarbothioamide (1204740-42-0) + zinc diacetate (557-34-6) → bis(5-methoxyisatin-3-(N-cyclohexyl)thiosemicarbazonato)zinc(II) hydrate

Guidance literature:

In ethanol; hot EtOH soln. of ligand added to soln. of Zn(CH3CO2)2, refluxed for 8-9h; isolated, washed with EtOH, Et2O; elem. anal.;

DOI:10.1016/j.molstruc.2009.09.009

upstream raw materials:

5-methoxyisatine

4-cyclohexyl-thiosemicarbazide