methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Base Information

Chemical Name:methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester
CAS No.:1266211-75-9
Molecular Formula:C₃₇H₅₃N₃O₁₇
Molecular Weight:811.838
Hs Code.:

Synonyms:methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Suppliers and Price of methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

There total 4 articles about methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1266211-74-8
methyl 3,4,6-tri-O-acetyl-2-deoxy-2-trichloroacetamido-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

: 1266211-75-9
methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Guidance literature:: methyl 3,4,6-tri-O-acetyl-2-deoxy-2-trichloroacetamido-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester; With 2,2'-azobis(isobutyronitrile); In N,N-dimethyl acetamide; at 90 ℃; for 1h; Inert atmosphere;

With tri-n-butyl-tin hydride; In N,N-dimethyl acetamide; at 90 ℃; Inert atmosphere;
DOI:10.1021/jo102329c

Reference yield:

: 1266211-66-8
methyl 4,6-O-benzylidene-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

: 1266211-75-9
methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylsilane / dichloromethane / -78 °C / Molecular sieve; Inert atmosphere

1.2: 1.5 h / -78 °C / Inert atmosphere; Molecular sieve

2.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0 - 20 °C / Molecular sieve; Inert atmosphere

3.1: 2,2'-azobis(isobutyronitrile) / N,N-dimethyl acetamide / 1 h / 90 °C / Inert atmosphere

3.2: 90 °C / Inert atmosphere

With triethylsilane; 2,2'-azobis(isobutyronitrile); trimethylsilyl trifluoromethanesulfonate; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/jo102329c

Reference yield:

: 1266211-68-0
methyl 6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

: 1266211-75-9
methyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-glucopyranosyl-(1->4)-6-O-benzyl-β-D-N-acetylmuramylpyranoside-L-alanine methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 0 - 20 °C / Molecular sieve; Inert atmosphere

2.1: 2,2'-azobis(isobutyronitrile) / N,N-dimethyl acetamide / 1 h / 90 °C / Inert atmosphere

2.2: 90 °C / Inert atmosphere

With 2,2'-azobis(isobutyronitrile); trimethylsilyl trifluoromethanesulfonate; In dichloromethane; N,N-dimethyl acetamide;
DOI:10.1021/jo102329c