(2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate

Base Information

• Chemical Name: (2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate
• CAS No.: 1327310-45-1
• Molecular Formula: C₁₃H₁₅BrO₄
• Molecular Weight: 315.164
• Mol file: 1327310-45-1.mol

Synonyms:(2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate

Chemical Property of (2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of (2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate

There total 1 articles about (2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-bromophenylacetic acid (4870-65-9,31302-84-8) + (S)-Ethyl lactate (687-47-8) → (2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate (1327310-45-1)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide;

DOI:10.5012/bkcs.2013.34.8.2531

Reference yield: 76.0%

(2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate (1327310-45-1) + benzylamine (100-46-9) → C20H23NO4 + C20H23NO4

Guidance literature:

With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0039-1691406

Reference yield: 76.0%

(2-ethoxy-(S)-1-methyl-2-oxoethyl) 2-bromo-2-phenylacetate (1327310-45-1) + isobutylamine (78-81-9) → C17H25NO4 + C17H25NO4

Guidance literature:

With tetra-(n-butyl)ammonium iodide; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1055/s-0039-1691406

upstream raw materials:

2-bromophenylacetic acid

(S)-Ethyl lactate

Downstream raw materials:

(S)-3-phenyl-2-piperazinone

(R)-3-phenyl-2-piperazinone

1,4-dibenzyl-(S)-3-phenyl-2-piperazinone

1,4-dibenzyl-(R)-3-phenyl-2-piperazinone