(S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Base Information

• Chemical Name: (S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate
• CAS No.: 1388220-72-1
• Molecular Formula: C₁₉H₂₇NO₅
• Molecular Weight: 349.427
• Mol file: 1388220-72-1.mol

Synonyms:(S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Chemical Property of (S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate

There total 1 articles about (S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(prop-2-en-1-yloxy)phenyl]-propanoate (147363-23-3) + methyl iodide (74-88-4) → (S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate (1388220-72-1)

Guidance literature:

With silver(l) oxide; In N,N-dimethyl-formamide; at 20 ℃; for 9h; Inert atmosphere;

DOI:10.1016/j.tetasy.2012.05.013

Reference yield:

(S)-methyl 3-[4-(allyloxy)phenyl]-2-[tert-butoxycarbonyl(methyl)amino]propanoate (1388220-72-1) → C18H25NO6

Guidance literature:

With 2,6-dimethylpyridine; sodium periodate; osmium(VIII) oxide; In 1,4-dioxane; water; toluene; at 20 ℃; for 4h; Inert atmosphere;

DOI:10.1016/j.tetasy.2012.05.013

upstream raw materials:

methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}-3-[4-(prop-2-en-1-yloxy)phenyl]-propanoate

methyl iodide