trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide

Base Information

• Chemical Name: trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide
• CAS No.: 120278-03-7
• Molecular Formula: BrH*C₁₂H₁₉BrN₄O₃
• Molecular Weight: 428.124
• Mol file: 120278-03-7.mol

Synonyms:trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide

Chemical Property of trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide

There total 3 articles about trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

α-[(2-Nitro-1H-imidazol-1-yl)methyl]-7-aza-bicyclo[4.1.0]heptane-7-ethanol (120277-90-9) → trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide (120278-03-7)

Guidance literature:

With hydrogen bromide; In ethanol; Heating;

DOI:10.1021/jm00112a026

Reference yield:

7-azabicyclo[4.1.0]heptane (286-18-0) → trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide (120278-03-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / methanol / 3 h / Heating

2: 93 percent / HBr / ethanol / Heating

With hydrogen bromide; In methanol; ethanol;

DOI:10.1021/jm00112a026

Reference yield:

2-nitro-1-(2-oxiranylmethyl)-1H-imidazole (13551-90-1) → trans-α-<<(2-bromocyclohexyl)amino>methyl>-2-nitro-1H-imidazole-1-ethanol hydrobromide (120278-03-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / methanol / 3 h / Heating

2: 93 percent / HBr / ethanol / Heating

With hydrogen bromide; In methanol; ethanol;

DOI:10.1021/jm00112a026

upstream raw materials:

α-[(2-Nitro-1H-imidazol-1-yl)methyl]-7-aza-bicyclo[4.1.0]heptane-7-ethanol

7-azabicyclo[4.1.0]heptane

2-nitro-1-(2-oxiranylmethyl)-1H-imidazole